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RBPJ has not been detected as a mutational cancer driver

RBPJ
Ensembl id ENSG00000168214
Mutated samples
Coding Sequence 33 (0.5%)
Protein Affecting 18 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all RBPJ gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Renal clear cell carcinoma No 4 4 0.96
Cutaneous melanoma No 7 3 0.81
Head and neck squamous cell carcinoma No 3 2 0.53
Lung adenocarcinoma No 1 1 0.26
Bladder carcinoma No 1 1 1.02
Thyroid carcinoma No 1 1 0.31
Lower grade glioma No 2 1 0.59
Serous ovarian adenocarcinoma No 1 1 0.32
Colorectal adenocarcinoma No 1 1 0.44
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 1 1 0.68
Acute lymphocytic leukemia No 1 1 0.82
Hepatocarcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 4 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Stomach adenocarcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence