IntOGen - PTPRT gene cancer mutations

PTPRT is detected as a mutational cancer driver

PTPRT reports

Methods
Mutation distribution

Gene details

PTPRT
Ensembl ID ENSG00000196090 Transcript ID ENST00000373198 Protein ID ENSP00000362294
Cancer types where is driver 6 Cohorts where is driver 7 Mutated samples 30 Mutations 1,624
Mode of action Ambiguous
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence