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PTPRN has not been detected as a mutational cancer driver

PTPRN
Ensembl id ENSG00000054356
Mutated samples
Coding Sequence 84 (1.2%)
Protein Affecting 57 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PTPRN gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 22 14 3.79
Lung squamous cell carcinoma No 12 9 5.17
Lung adenocarcinoma No 10 7 1.79
Head and neck squamous cell carcinoma No 7 6 1.60
Breast carcinoma No 6 5 0.44
Stomach adenocarcinoma No 5 4 2.48
Bladder carcinoma No 2 2 2.04
Renal clear cell carcinoma No 2 2 0.48
Uterine corpus endometrioid carcinoma No 3 2 0.87
Small cell lung carcinoma No 2 2 2.90
Prostate adenocarcinoma No 2 1 0.41
Acute myeloid leukemia No 2 1 0.51
Colorectal adenocarcinoma No 2 1 0.44
Glioblastoma multiforme No 1 1 0.26
Thyroid carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Serous ovarian adenocarcinoma No 3 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence