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PRR23B has not been detected as a mutational cancer driver

PRR23B
Ensembl id ENSG00000184814
Mutated samples
Coding Sequence 62 (0.9%)
Protein Affecting 44 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PRR23B gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 28 20 5.42
Lung squamous cell carcinoma No 10 9 5.17
Lung adenocarcinoma No 5 2 0.51
Breast carcinoma No 2 2 0.17
Uterine corpus endometrioid carcinoma No 4 2 0.87
Stomach adenocarcinoma No 2 2 1.24
Glioblastoma multiforme No 3 2 0.53
Bladder carcinoma No 1 1 1.02
Neuroblastoma No 1 1 0.48
Lower grade glioma No 1 1 0.59
Head and neck squamous cell carcinoma No 2 1 0.27
Esophageal carcinoma No 1 1 0.68
Chronic lymphocytic leukemia No 1 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence