IntOGen - PRDM1 gene cancer mutations

PRDM1 is detected as a mutational cancer driver

PRDM1 reports

Methods
Mutation distribution

Gene details

PRDM1
Ensembl ID ENSG00000057657 Transcript ID ENST00000369096 Protein ID ENSP00000358092
Cancer types where is driver 5 Cohorts where is driver 7 Mutated samples 57 Mutations 483
Mode of action Ambiguous
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence