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POTEF has not been detected as a mutational cancer driver

POTEF
Ensembl id ENSG00000196604
Mutated samples
Coding Sequence 124 (1.8%)
Protein Affecting 87 (1.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all POTEF gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 48 28 7.59
Lung adenocarcinoma No 20 13 3.32
Lung squamous cell carcinoma No 10 10 5.75
Uterine corpus endometrioid carcinoma No 9 7 3.04
Breast carcinoma No 5 5 0.44
Glioblastoma multiforme No 6 5 1.32
Head and neck squamous cell carcinoma No 7 4 1.07
Prostate adenocarcinoma No 2 2 0.82
Renal clear cell carcinoma No 2 2 0.48
Serous ovarian adenocarcinoma No 3 2 0.63
Stomach adenocarcinoma No 2 2 1.24
Esophageal carcinoma No 2 2 1.37
Bladder carcinoma No 3 1 1.02
Thyroid carcinoma No 1 1 0.31
Neuroblastoma No 1 1 0.48
Lower grade glioma No 2 1 0.59
Colorectal adenocarcinoma No 1 1 0.44
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence