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PIK3CD has not been detected as a mutational cancer driver

PIK3CD
Ensembl id ENSG00000171608
Mutated samples
Coding Sequence 84 (1.2%)
Protein Affecting 38 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PIK3CD gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 16 7 1.90
Stomach adenocarcinoma No 9 6 3.73
Uterine corpus endometrioid carcinoma No 8 5 2.17
Breast carcinoma No 7 4 0.35
Lung adenocarcinoma No 9 3 0.77
Lung squamous cell carcinoma No 9 3 1.72
Head and neck squamous cell carcinoma No 6 3 0.80
Prostate adenocarcinoma No 1 1 0.41
Bladder carcinoma No 1 1 1.02
Medulloblastoma No 1 1 0.48
Pancreas adenocarcinoma No 2 1 0.47
Small cell lung carcinoma No 1 1 1.45
Diffuse B cell lymphoma No 1 1 4.35
Esophageal carcinoma No 3 1 0.68
Hepatocarcinoma No 2 0 0.00
Thyroid carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Multiple myeloma No 1 0 0.00
Lower grade glioma No 1 0 0.00
Colorectal adenocarcinoma No 2 0 0.00
Glioblastoma multiforme No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence