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PCDH7 has not been detected as a mutational cancer driver

PCDH7
Ensembl id ENSG00000169851
Mutated samples
Coding Sequence 106 (1.6%)
Protein Affecting 66 (1.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PCDH7 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung squamous cell carcinoma No 12 11 6.32
Lung adenocarcinoma No 12 8 2.05
Cutaneous melanoma No 13 8 2.17
Renal clear cell carcinoma No 6 6 1.44
Head and neck squamous cell carcinoma No 8 5 1.33
Breast carcinoma No 5 4 0.35
Stomach adenocarcinoma No 7 4 2.48
Glioblastoma multiforme No 6 4 1.06
Colorectal adenocarcinoma No 3 3 1.31
Hepatocarcinoma No 2 2 2.22
Bladder carcinoma No 2 2 2.04
Lower grade glioma No 2 2 1.18
Small cell lung carcinoma No 2 2 2.90
Esophageal carcinoma No 3 2 1.37
Uterine corpus endometrioid carcinoma No 1 1 0.43
Multiple myeloma No 1 1 1.45
Serous ovarian adenocarcinoma No 2 1 0.32
Non small cell lung carcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 14 0 0.00
Pylocytic astrocytoma No 2 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence