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PCBP1 is detected as a mutational cancer driver in 1 cancer type: Colorectal adenocarcinoma

PCBP1
Ensembl id ENSG00000169564
Mutated samples
Coding Sequence 18 (0.3%)
Protein Affecting 12 (0.2%)
Mode of action Activating
Known driver No
Cancer type Signals (Biases)
COREAD F
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PCBP1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Colorectal adenocarcinoma Yes 5 5 2.18
Uterine corpus endometrioid carcinoma No 2 2 0.87
Lung adenocarcinoma No 1 1 0.26
Bladder carcinoma No 2 1 1.02
Renal clear cell carcinoma No 1 1 0.24
Stomach adenocarcinoma No 1 1 0.62
Esophageal carcinoma No 2 1 0.68
Cutaneous melanoma No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Head and neck squamous cell carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence