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P2RY12 has not been detected as a mutational cancer driver

P2RY12
Ensembl id ENSG00000169313
Mutated samples
Coding Sequence 113 (1.7%)
Protein Affecting 18 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all P2RY12 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Stomach adenocarcinoma No 11 5 3.11
Lung adenocarcinoma No 15 2 0.51
Cutaneous melanoma No 28 2 0.54
Uterine corpus endometrioid carcinoma No 5 2 0.87
Esophageal carcinoma No 5 2 1.37
Breast carcinoma No 7 1 0.09
Renal clear cell carcinoma No 3 1 0.24
Lower grade glioma No 1 1 0.59
Serous ovarian adenocarcinoma No 5 1 0.32
Colorectal adenocarcinoma No 4 1 0.44
Prostate adenocarcinoma No 1 0 0.00
Hepatocarcinoma No 2 0 0.00
Bladder carcinoma No 2 0 0.00
Lung squamous cell carcinoma No 7 0 0.00
Neuroblastoma No 1 0 0.00
Non small cell lung carcinoma No 3 0 0.00
Multiple myeloma No 1 0 0.00
Small cell lung carcinoma No 1 0 0.00
Head and neck squamous cell carcinoma No 10 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence