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OR1C1 has not been detected as a mutational cancer driver

OR1C1
Ensembl id ENSG00000221888
Mutated samples
Coding Sequence 83 (1.2%)
Protein Affecting 50 (0.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all OR1C1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 19 11 2.81
Cutaneous melanoma No 21 9 2.44
Lung squamous cell carcinoma No 10 7 4.02
Head and neck squamous cell carcinoma No 6 4 1.07
Esophageal carcinoma No 4 4 2.74
Lower grade glioma No 3 3 1.78
Small cell lung carcinoma No 3 3 4.35
Bladder carcinoma No 2 2 2.04
Medulloblastoma No 2 2 0.95
Colorectal adenocarcinoma No 2 2 0.87
Renal clear cell carcinoma No 2 1 0.24
Non small cell lung carcinoma No 1 1 3.23
Glioblastoma multiforme No 2 1 0.26
Hepatocarcinoma No 2 0 0.00
Acute myeloid leukemia No 1 0 0.00
Uterine corpus endometrioid carcinoma No 1 0 0.00
Stomach adenocarcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence