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OLFM3 has not been detected as a mutational cancer driver

OLFM3
Ensembl id ENSG00000118733
Mutated samples
Coding Sequence 97 (1.4%)
Protein Affecting 70 (1.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all OLFM3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 28 22 5.96
Head and neck squamous cell carcinoma No 13 10 2.67
Lung adenocarcinoma No 10 9 2.30
Lung squamous cell carcinoma No 7 7 4.02
Esophageal carcinoma No 8 5 3.42
Colorectal adenocarcinoma No 4 4 1.75
Serous ovarian adenocarcinoma No 3 3 0.95
Bladder carcinoma No 2 2 2.04
Renal clear cell carcinoma No 2 2 0.48
Hepatocarcinoma No 4 1 1.11
Breast carcinoma No 1 1 0.09
Lower grade glioma No 1 1 0.59
Stomach adenocarcinoma No 4 1 0.62
Small cell lung carcinoma No 3 1 1.45
Acute lymphocytic leukemia No 1 1 0.82
Prostate adenocarcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Pylocytic astrocytoma No 2 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence