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NUP210L has not been detected as a mutational cancer driver

NUP210L
Ensembl id ENSG00000143552
Mutated samples
Coding Sequence 141 (2.1%)
Protein Affecting 101 (1.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all NUP210L gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 48 35 9.49
Lung squamous cell carcinoma No 17 14 8.05
Glioblastoma multiforme No 9 9 2.37
Breast carcinoma No 9 7 0.61
Lung adenocarcinoma No 8 6 1.53
Head and neck squamous cell carcinoma No 9 6 1.60
Renal clear cell carcinoma No 8 4 0.96
Serous ovarian adenocarcinoma No 3 3 0.95
Stomach adenocarcinoma No 6 3 1.86
Bladder carcinoma No 4 2 2.04
Non small cell lung carcinoma No 2 2 6.45
Lower grade glioma No 2 2 1.18
Prostate adenocarcinoma No 1 1 0.41
Pancreas adenocarcinoma No 1 1 0.47
Thyroid carcinoma No 2 1 0.31
Uterine corpus endometrioid carcinoma No 3 1 0.43
Chronic lymphocytic leukemia No 2 1 0.34
Small cell lung carcinoma No 1 1 1.45
Colorectal adenocarcinoma No 2 1 0.44
Esophageal carcinoma No 2 1 0.68
Neuroblastoma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence