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NFXL1 has not been detected as a mutational cancer driver

NFXL1
Ensembl id ENSG00000170448
Mutated samples
Coding Sequence 55 (0.8%)
Protein Affecting 44 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all NFXL1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 18 17 4.61
Renal clear cell carcinoma No 4 4 0.96
Head and neck squamous cell carcinoma No 5 4 1.07
Lung adenocarcinoma No 5 3 0.77
Lung squamous cell carcinoma No 3 3 1.72
Breast carcinoma No 2 2 0.17
Colorectal adenocarcinoma No 3 2 0.87
Glioblastoma multiforme No 2 2 0.53
Esophageal carcinoma No 2 2 1.37
Thyroid carcinoma No 1 1 0.31
Uterine corpus endometrioid carcinoma No 2 1 0.43
Non small cell lung carcinoma No 1 1 3.23
Serous ovarian adenocarcinoma No 1 1 0.32
Stomach adenocarcinoma No 3 1 0.62
Hepatocarcinoma No 3 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence