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NEXN has not been detected as a mutational cancer driver

NEXN
Ensembl id ENSG00000162614
Mutated samples
Coding Sequence 58 (0.9%)
Protein Affecting 44 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all NEXN gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 18 13 3.52
Breast carcinoma No 5 5 0.44
Head and neck squamous cell carcinoma No 6 4 1.07
Uterine corpus endometrioid carcinoma No 4 3 1.30
Lung squamous cell carcinoma No 2 2 1.15
Thyroid carcinoma No 2 2 0.62
Serous ovarian adenocarcinoma No 2 2 0.63
Stomach adenocarcinoma No 3 2 1.24
Colorectal adenocarcinoma No 2 2 0.87
Glioblastoma multiforme No 2 2 0.53
Lung adenocarcinoma No 1 1 0.26
Hepatocarcinoma No 1 1 1.11
Bladder carcinoma No 1 1 1.02
Medulloblastoma No 2 1 0.48
Renal clear cell carcinoma No 2 1 0.24
Non small cell lung carcinoma No 1 1 3.23
Small cell lung carcinoma No 1 1 1.45
Chronic lymphocytic leukemia No 2 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence