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NEIL1 has not been detected as a mutational cancer driver

NEIL1
Ensembl id ENSG00000140398
Mutated samples
Coding Sequence 58 (0.9%)
Protein Affecting 18 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all NEIL1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Breast carcinoma No 7 5 0.44
Uterine corpus endometrioid carcinoma No 7 3 1.30
Lung squamous cell carcinoma No 5 2 1.15
Head and neck squamous cell carcinoma No 5 2 0.53
Lung adenocarcinoma No 5 1 0.26
Bladder carcinoma No 2 1 1.02
Cutaneous melanoma No 12 1 0.27
Neuroblastoma No 1 1 0.48
Colorectal adenocarcinoma No 1 1 0.44
Esophageal carcinoma No 2 1 0.68
Hepatocarcinoma No 1 0 0.00
Medulloblastoma No 1 0 0.00
Renal clear cell carcinoma No 2 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Stomach adenocarcinoma No 4 0 0.00
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence