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NDNF has not been detected as a mutational cancer driver

NDNF
Ensembl id ENSG00000173376
Mutated samples
Coding Sequence 62 (0.9%)
Protein Affecting 45 (0.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all NDNF gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 22 15 4.07
Head and neck squamous cell carcinoma No 10 8 2.13
Breast carcinoma No 5 4 0.35
Lung squamous cell carcinoma No 5 3 1.72
Stomach adenocarcinoma No 4 3 1.86
Small cell lung carcinoma No 3 3 4.35
Uterine corpus endometrioid carcinoma No 2 2 0.87
Esophageal carcinoma No 3 2 1.37
Prostate adenocarcinoma No 2 1 0.41
Lung adenocarcinoma No 1 1 0.26
Bladder carcinoma No 1 1 1.02
Renal clear cell carcinoma No 1 1 0.24
Lower grade glioma No 1 1 0.59
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence