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NBEAL2 has not been detected as a mutational cancer driver

NBEAL2
Ensembl id ENSG00000160796
Mutated samples
Coding Sequence 101 (1.5%)
Protein Affecting 76 (1.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all NBEAL2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 27 18 4.88
Breast carcinoma No 10 10 0.87
Uterine corpus endometrioid carcinoma No 9 8 3.48
Stomach adenocarcinoma No 8 6 3.73
Head and neck squamous cell carcinoma No 7 5 1.33
Lung adenocarcinoma No 4 4 1.02
Lung squamous cell carcinoma No 4 4 2.30
Chronic lymphocytic leukemia No 3 3 1.03
Serous ovarian adenocarcinoma No 4 3 0.95
Colorectal adenocarcinoma No 3 3 1.31
Thyroid carcinoma No 2 2 0.62
Glioblastoma multiforme No 3 2 0.53
Esophageal carcinoma No 2 2 1.37
Hepatocarcinoma No 1 1 1.11
Pancreas adenocarcinoma No 1 1 0.47
Renal clear cell carcinoma No 4 1 0.24
Neuroblastoma No 1 1 0.48
Lower grade glioma No 1 1 0.59
Acute lymphocytic leukemia No 1 1 0.82
Prostate adenocarcinoma No 2 0 0.00
Bladder carcinoma No 1 0 0.00
Medulloblastoma No 1 0 0.00
Multiple myeloma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence