IntOGen - MUC6 gene cancer mutations

MUC6 is detected as a mutational cancer driver

MUC6 reports

Methods
Mutation distribution

Gene details

MUC6
Ensembl ID ENSG00000184956 Transcript ID ENST00000421673 Protein ID ENSP00000406861
Cancer types where is driver 5 Cohorts where is driver 5 Mutated samples 116 Mutations 1,510
Mode of action Activating
Known driver False

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence