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MTX1 has not been detected as a mutational cancer driver

MTX1
Ensembl id ENSG00000173171
Mutated samples
Coding Sequence 45 (0.7%)
Protein Affecting 12 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MTX1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung squamous cell carcinoma No 2 2 1.15
Uterine corpus endometrioid carcinoma No 3 2 0.87
Stomach adenocarcinoma No 3 2 1.24
Prostate adenocarcinoma No 1 1 0.41
Breast carcinoma No 7 1 0.09
Thyroid carcinoma No 1 1 0.31
Cutaneous melanoma No 11 1 0.27
Colorectal adenocarcinoma No 1 1 0.44
Head and neck squamous cell carcinoma No 3 1 0.27
Lung adenocarcinoma No 3 0 0.00
Hepatocarcinoma No 2 0 0.00
Bladder carcinoma No 2 0 0.00
Renal clear cell carcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
Glioblastoma multiforme No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence