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MOV10 has not been detected as a mutational cancer driver

MOV10
Ensembl id ENSG00000155363
Mutated samples
Coding Sequence 65 (1.0%)
Protein Affecting 36 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MOV10 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 17 9 2.44
Lung adenocarcinoma No 4 4 1.02
Breast carcinoma No 5 3 0.26
Serous ovarian adenocarcinoma No 5 3 0.95
Stomach adenocarcinoma No 7 3 1.86
Bladder carcinoma No 2 2 2.04
Thyroid carcinoma No 2 2 0.62
Uterine corpus endometrioid carcinoma No 4 2 0.87
Glioblastoma multiforme No 2 2 0.53
Lung squamous cell carcinoma No 4 1 0.57
Renal clear cell carcinoma No 2 1 0.24
Small cell lung carcinoma No 1 1 1.45
Colorectal adenocarcinoma No 3 1 0.44
Head and neck squamous cell carcinoma No 4 1 0.27
Esophageal carcinoma No 1 1 0.68
Prostate adenocarcinoma No 1 0 0.00
Neuroblastoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence