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MNDA is detected as a mutational cancer driver in 1 cancer type: Small cell lung carcinoma

MNDA
Ensembl id ENSG00000163563
Mutated samples
Coding Sequence 82 (1.2%)
Protein Affecting 68 (1.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
SCLC F
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MNDA gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Small cell lung carcinoma Yes 6 6 8.70
Cutaneous melanoma No 20 15 4.07
Lung squamous cell carcinoma No 8 7 4.02
Lung adenocarcinoma No 7 6 1.53
Uterine corpus endometrioid carcinoma No 8 6 2.61
Stomach adenocarcinoma No 6 5 3.11
Breast carcinoma No 5 4 0.35
Head and neck squamous cell carcinoma No 6 4 1.07
Esophageal carcinoma No 3 3 2.05
Neuroblastoma No 2 2 0.95
Serous ovarian adenocarcinoma No 2 2 0.63
Hepatocarcinoma No 1 1 1.11
Bladder carcinoma No 1 1 1.02
Acute myeloid leukemia No 1 1 0.51
Pancreas adenocarcinoma No 1 1 0.47
Renal clear cell carcinoma No 1 1 0.24
Non small cell lung carcinoma No 1 1 3.23
Chronic lymphocytic leukemia No 1 1 0.34
Glioblastoma multiforme No 1 1 0.26
Colorectal adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence