IntOGen - MLLT6 gene cancer mutations

MLLT6 is detected as a mutational cancer driver

MLLT6 reports

Methods
Mutation distribution

Gene details

MLLT6
Ensembl ID ENSG00000275023 Transcript ID ENST00000621332 Protein ID ENSP00000479910
Cancer types where is driver 1 Cohorts where is driver 1 Mutated samples 3 Mutations 320
Mode of action Activating
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence