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MFAP3L has not been detected as a mutational cancer driver

MFAP3L
Ensembl id ENSG00000198948
Mutated samples
Coding Sequence 35 (0.5%)
Protein Affecting 21 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MFAP3L gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 6 4 1.02
Breast carcinoma No 4 3 0.26
Stomach adenocarcinoma No 7 3 1.86
Renal clear cell carcinoma No 2 2 0.48
Cutaneous melanoma No 2 2 0.54
Uterine corpus endometrioid carcinoma No 4 2 0.87
Serous ovarian adenocarcinoma No 2 2 0.63
Small cell lung carcinoma No 2 1 1.45
Head and neck squamous cell carcinoma No 1 1 0.27
Glioblastoma multiforme No 1 1 0.26
Prostate adenocarcinoma No 1 0 0.00
Thyroid carcinoma No 1 0 0.00
Neuroblastoma No 1 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence