Top
METTL21A has not been detected as a mutational cancer driver

METTL21A
Ensembl id ENSG00000144401
Mutated samples
Coding Sequence 23 (0.3%)
Protein Affecting 15 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all METTL21A gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 3 2 0.51
Cutaneous melanoma No 2 2 0.54
Stomach adenocarcinoma No 2 2 1.24
Hepatocarcinoma No 3 1 1.11
Bladder carcinoma No 1 1 1.02
Breast carcinoma No 2 1 0.09
Lung squamous cell carcinoma No 1 1 0.57
Uterine corpus endometrioid carcinoma No 1 1 0.43
Non small cell lung carcinoma No 1 1 3.23
Serous ovarian adenocarcinoma No 1 1 0.32
Small cell lung carcinoma No 1 1 1.45
Head and neck squamous cell carcinoma No 2 1 0.27
Renal clear cell carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence