MAB21L2 has not been detected as a mutational cancer driver

Ensembl id ENSG00000181541
Mutated samples
Coding Sequence 40 (0.6%)
Protein Affecting 21 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MAB21L2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Uterine corpus endometrioid carcinoma No 7 5 2.17
Cutaneous melanoma No 10 4 1.08
Head and neck squamous cell carcinoma No 6 3 0.80
Lung adenocarcinoma No 5 2 0.51
Colorectal adenocarcinoma No 3 2 0.87
Breast carcinoma No 2 1 0.09
Renal clear cell carcinoma No 1 1 0.24
Lower grade glioma No 1 1 0.59
Serous ovarian adenocarcinoma No 1 1 0.32
Esophageal carcinoma No 1 1 0.68
Lung squamous cell carcinoma No 2 0 0.00
Stomach adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence