LRP1B is detected as a mutational cancer driver in Glioblastoma Multiforme
LRP1B reports in Glioblastoma Multiforme (GBM)
Cancer type details
| Glioblastoma Multiforme |
|---|
|
Cohorts
5
Samples 673 Mutations 3,702,787 Driver genes 52 |
Gene details
| LRP1B |
|---|
|
Ensembl ID
ENSG00000168702
Transcript ID ENST00000389484 Protein ID ENSP00000374135 |
|
Cohorts where is driver
3
Mutated samples 13 Mutated samples (%) 1.93 Mutations 31 |
| Mode of action Ambiguous |
| Known driver True |
Method signals per Cohort
| Cohort | Methods | Samples | Samples (%) |
|---|
ClustL
HotMAPS
smRegions
Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed
mutations along the protein sequence.
| Mutation (GRCh38) | Protein Position | Samples | Samples (%) | Consequence |
|---|