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LCORL has not been detected as a mutational cancer driver

LCORL
Ensembl id ENSG00000178177
Mutated samples
Coding Sequence 26 (0.4%)
Protein Affecting 10 (0.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all LCORL gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Breast carcinoma No 2 2 0.17
Renal clear cell carcinoma No 2 2 0.48
Stomach adenocarcinoma No 2 2 1.24
Head and neck squamous cell carcinoma No 4 2 0.53
Lung adenocarcinoma No 1 1 0.26
Uterine corpus endometrioid carcinoma No 2 1 0.43
Hepatocarcinoma No 1 0 0.00
Lung squamous cell carcinoma No 1 0 0.00
Cutaneous melanoma No 4 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Lower grade glioma No 1 0 0.00
Small cell lung carcinoma No 2 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence