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KNG1 has not been detected as a mutational cancer driver

KNG1
Ensembl id ENSG00000113889
Mutated samples
Coding Sequence 61 (0.9%)
Protein Affecting 51 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all KNG1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 20 16 4.34
Lung squamous cell carcinoma No 8 7 4.02
Stomach adenocarcinoma No 5 5 3.11
Breast carcinoma No 4 4 0.35
Lung adenocarcinoma No 3 3 0.77
Small cell lung carcinoma No 3 3 4.35
Renal clear cell carcinoma No 2 2 0.48
Uterine corpus endometrioid carcinoma No 2 2 0.87
Head and neck squamous cell carcinoma No 4 2 0.53
Glioblastoma multiforme No 2 2 0.53
Bladder carcinoma No 1 1 1.02
Pancreas adenocarcinoma No 1 1 0.47
Neuroblastoma No 1 1 0.48
Non small cell lung carcinoma No 1 1 3.23
Serous ovarian adenocarcinoma No 1 1 0.32
Hepatocarcinoma No 3 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence