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KIF15 has not been detected as a mutational cancer driver

KIF15
Ensembl id ENSG00000163808
Mutated samples
Coding Sequence 79 (1.2%)
Protein Affecting 50 (0.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all KIF15 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 26 14 3.79
Bladder carcinoma No 4 4 4.08
Renal clear cell carcinoma No 4 4 0.96
Lung adenocarcinoma No 4 3 0.77
Uterine corpus endometrioid carcinoma No 5 3 1.30
Stomach adenocarcinoma No 5 3 1.86
Esophageal carcinoma No 6 3 2.05
Lung squamous cell carcinoma No 4 2 1.15
Chronic lymphocytic leukemia No 3 2 0.69
Colorectal adenocarcinoma No 3 2 0.87
Hepatocarcinoma No 2 1 1.11
Breast carcinoma No 2 1 0.09
Medulloblastoma No 1 1 0.48
Thyroid carcinoma No 1 1 0.31
Neuroblastoma No 1 1 0.48
Non small cell lung carcinoma No 1 1 3.23
Serous ovarian adenocarcinoma No 1 1 0.32
Small cell lung carcinoma No 2 1 1.45
Head and neck squamous cell carcinoma No 3 1 0.27
Glioblastoma multiforme No 1 1 0.26
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence