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KCNN3 has not been detected as a mutational cancer driver

KCNN3
Ensembl id ENSG00000143603
Mutated samples
Coding Sequence 82 (1.2%)
Protein Affecting 46 (0.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all KCNN3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 27 18 4.88
Lung adenocarcinoma No 7 7 1.79
Bladder carcinoma No 4 3 3.06
Lung squamous cell carcinoma No 6 3 1.72
Uterine corpus endometrioid carcinoma No 5 3 1.30
Breast carcinoma No 7 2 0.17
Renal clear cell carcinoma No 3 2 0.48
Stomach adenocarcinoma No 2 2 1.24
Small cell lung carcinoma No 2 2 2.90
Prostate adenocarcinoma No 1 1 0.41
Acute myeloid leukemia No 1 1 0.51
Thyroid carcinoma No 4 1 0.31
Colorectal adenocarcinoma No 3 1 0.44
Neuroblastoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Lower grade glioma No 1 0 0.00
Head and neck squamous cell carcinoma No 6 0 0.00
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence