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KCNH7 has not been detected as a mutational cancer driver

KCNH7
Ensembl id ENSG00000184611
Mutated samples
Coding Sequence 202 (3.0%)
Protein Affecting 154 (2.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all KCNH7 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 69 50 13.55
Lung adenocarcinoma No 18 15 3.84
Lung squamous cell carcinoma No 14 12 6.90
Head and neck squamous cell carcinoma No 13 11 2.93
Small cell lung carcinoma No 12 9 13.04
Breast carcinoma No 9 8 0.70
Stomach adenocarcinoma No 10 8 4.97
Renal clear cell carcinoma No 6 6 1.44
Uterine corpus endometrioid carcinoma No 6 6 2.61
Colorectal adenocarcinoma No 5 5 2.18
Esophageal carcinoma No 5 5 3.42
Bladder carcinoma No 4 4 4.08
Serous ovarian adenocarcinoma No 3 3 0.95
Hepatocarcinoma No 3 2 2.22
Multiple myeloma No 2 2 2.90
Lower grade glioma No 2 2 1.18
Glioblastoma multiforme No 2 2 0.53
Prostate adenocarcinoma No 2 1 0.41
Thyroid carcinoma No 1 1 0.31
Non small cell lung carcinoma No 2 1 3.23
Chronic lymphocytic leukemia No 14 1 0.34
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence