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JAKMIP1 has not been detected as a mutational cancer driver

JAKMIP1
Ensembl id ENSG00000152969
Mutated samples
Coding Sequence 114 (1.7%)
Protein Affecting 75 (1.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all JAKMIP1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 39 26 7.05
Head and neck squamous cell carcinoma No 11 10 2.67
Stomach adenocarcinoma No 9 7 4.35
Lung adenocarcinoma No 8 6 1.53
Breast carcinoma No 9 4 0.35
Lung squamous cell carcinoma No 7 4 2.30
Colorectal adenocarcinoma No 6 4 1.75
Bladder carcinoma No 4 2 2.04
Pancreas adenocarcinoma No 2 2 0.93
Renal clear cell carcinoma No 2 2 0.48
Prostate adenocarcinoma No 1 1 0.41
Neuroblastoma No 1 1 0.48
Uterine corpus endometrioid carcinoma No 1 1 0.43
Chronic lymphocytic leukemia No 6 1 0.34
Serous ovarian adenocarcinoma No 1 1 0.32
Glioblastoma multiforme No 2 1 0.26
Esophageal carcinoma No 2 1 0.68
Acute lymphocytic leukemia No 1 1 0.82
Non small cell lung carcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence