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ITGA9 is detected as a mutational cancer driver in 1 cancer type: Cutaneous melanoma

ITGA9
Ensembl id ENSG00000144668
Mutated samples
Coding Sequence 73 (1.1%)
Protein Affecting 50 (0.7%)
Mode of action Activating
Known driver No
Cancer type Signals (Biases)
CM F
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ITGA9 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma Yes 20 17 4.61
Stomach adenocarcinoma No 7 6 3.73
Breast carcinoma No 5 4 0.35
Uterine corpus endometrioid carcinoma No 4 3 1.30
Bladder carcinoma No 2 2 2.04
Lung squamous cell carcinoma No 3 2 1.15
Renal clear cell carcinoma No 2 2 0.48
Multiple myeloma No 2 2 2.90
Small cell lung carcinoma No 2 2 2.90
Glioblastoma multiforme No 3 2 0.53
Esophageal carcinoma No 3 2 1.37
Prostate adenocarcinoma No 1 1 0.41
Lung adenocarcinoma No 1 1 0.26
Pancreas adenocarcinoma No 1 1 0.47
Chronic lymphocytic leukemia No 9 1 0.34
Colorectal adenocarcinoma No 2 1 0.44
Head and neck squamous cell carcinoma No 3 1 0.27
Hepatocarcinoma No 2 0 0.00
Medulloblastoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence