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INTS12 has not been detected as a mutational cancer driver

INTS12
Ensembl id ENSG00000138785
Mutated samples
Coding Sequence 72 (1.1%)
Protein Affecting 23 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all INTS12 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Head and neck squamous cell carcinoma No 7 5 1.33
Breast carcinoma No 6 4 0.35
Lung adenocarcinoma No 5 3 0.77
Bladder carcinoma No 3 2 2.04
Cutaneous melanoma No 19 2 0.54
Uterine corpus endometrioid carcinoma No 4 2 0.87
Prostate adenocarcinoma No 1 1 0.41
Multiple myeloma No 2 1 1.45
Small cell lung carcinoma No 1 1 1.45
Colorectal adenocarcinoma No 3 1 0.44
Glioblastoma multiforme No 2 1 0.26
Hepatocarcinoma No 1 0 0.00
Acute myeloid leukemia No 1 0 0.00
Medulloblastoma No 3 0 0.00
Lung squamous cell carcinoma No 1 0 0.00
Renal clear cell carcinoma No 3 0 0.00
Chronic lymphocytic leukemia No 3 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
Stomach adenocarcinoma No 2 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
Esophageal carcinoma No 3 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence