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IL12A has not been detected as a mutational cancer driver

IL12A
Ensembl id ENSG00000168811
Mutated samples
Coding Sequence 22 (0.3%)
Protein Affecting 14 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all IL12A gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 8 4 1.08
Breast carcinoma No 3 3 0.26
Uterine corpus endometrioid carcinoma No 3 3 1.30
Lung adenocarcinoma No 2 2 0.51
Lung squamous cell carcinoma No 1 1 0.57
Head and neck squamous cell carcinoma No 2 1 0.27
Prostate adenocarcinoma No 1 0 0.00
Neuroblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence