IntOGen - HOXC13 gene cancer mutations

HOXC13 is detected as a mutational cancer driver

HOXC13 reports

Methods
Mutation distribution

Gene details

HOXC13
Ensembl ID ENSG00000123364 Transcript ID ENST00000243056 Protein ID ENSP00000243056
Cancer types where is driver 1 Cohorts where is driver 1 Mutated samples 9 Mutations 150
Mode of action Loss of function
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence