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HECTD3 has not been detected as a mutational cancer driver

HECTD3
Ensembl id ENSG00000126107
Mutated samples
Coding Sequence 58 (0.9%)
Protein Affecting 32 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all HECTD3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 6 5 1.28
Stomach adenocarcinoma No 8 5 3.11
Uterine corpus endometrioid carcinoma No 7 4 1.74
Breast carcinoma No 3 3 0.26
Cutaneous melanoma No 10 3 0.81
Lung squamous cell carcinoma No 2 2 1.15
Renal clear cell carcinoma No 3 2 0.48
Small cell lung carcinoma No 2 2 2.90
Colorectal adenocarcinoma No 2 2 0.87
Prostate adenocarcinoma No 1 1 0.41
Bladder carcinoma No 2 1 1.02
Serous ovarian adenocarcinoma No 1 1 0.32
Head and neck squamous cell carcinoma No 6 1 0.27
Chronic lymphocytic leukemia No 1 0 0.00
Multiple myeloma No 1 0 0.00
Esophageal carcinoma No 3 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence