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HAO2 has not been detected as a mutational cancer driver

HAO2
Ensembl id ENSG00000116882
Mutated samples
Coding Sequence 46 (0.7%)
Protein Affecting 33 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all HAO2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 18 12 3.25
Uterine corpus endometrioid carcinoma No 6 5 2.17
Lung adenocarcinoma No 4 3 0.77
Breast carcinoma No 4 3 0.26
Head and neck squamous cell carcinoma No 4 3 0.80
Bladder carcinoma No 2 2 2.04
Chronic lymphocytic leukemia No 1 1 0.34
Serous ovarian adenocarcinoma No 1 1 0.32
Colorectal adenocarcinoma No 1 1 0.44
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 3 1 0.68
Renal clear cell carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence