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GPRIN3 has not been detected as a mutational cancer driver

GPRIN3
Ensembl id ENSG00000185477
Mutated samples
Coding Sequence 63 (0.9%)
Protein Affecting 46 (0.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all GPRIN3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 15 9 2.44
Head and neck squamous cell carcinoma No 7 6 1.60
Breast carcinoma No 7 5 0.44
Lung squamous cell carcinoma No 6 5 2.87
Serous ovarian adenocarcinoma No 4 4 1.27
Lung adenocarcinoma No 4 3 0.77
Uterine corpus endometrioid carcinoma No 3 3 1.30
Stomach adenocarcinoma No 3 3 1.86
Bladder carcinoma No 3 2 2.04
Neuroblastoma No 2 2 0.95
Prostate adenocarcinoma No 1 1 0.41
Renal clear cell carcinoma No 1 1 0.24
Thyroid carcinoma No 2 1 0.31
Colorectal adenocarcinoma No 1 1 0.44
Hepatocarcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Small cell lung carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence