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GOLGB1 has not been detected as a mutational cancer driver

GOLGB1
Ensembl id ENSG00000173230
Mutated samples
Coding Sequence 169 (2.5%)
Protein Affecting 137 (2.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all GOLGB1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 37 25 6.78
Breast carcinoma No 20 17 1.48
Lung squamous cell carcinoma No 14 13 7.47
Head and neck squamous cell carcinoma No 13 12 3.20
Bladder carcinoma No 10 9 9.18
Stomach adenocarcinoma No 11 9 5.59
Lung adenocarcinoma No 9 8 2.05
Uterine corpus endometrioid carcinoma No 8 7 3.04
Serous ovarian adenocarcinoma No 7 7 2.22
Esophageal carcinoma No 7 7 4.79
Small cell lung carcinoma No 4 4 5.80
Glioblastoma multiforme No 3 3 0.79
Hepatocarcinoma No 4 2 2.22
Medulloblastoma No 3 2 0.95
Renal clear cell carcinoma No 4 2 0.48
Thyroid carcinoma No 3 2 0.62
Chronic lymphocytic leukemia No 4 2 0.69
Colorectal adenocarcinoma No 2 2 0.87
Pancreas adenocarcinoma No 1 1 0.47
Neuroblastoma No 1 1 0.48
Non small cell lung carcinoma No 1 1 3.23
Lower grade glioma No 1 1 0.59
Prostate adenocarcinoma No 1 0 0.00
Acute myeloid leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence