IntOGen - GMPS gene cancer mutations

GMPS is detected as a mutational cancer driver

GMPS reports

Methods
Mutation distribution

Gene details

GMPS
Ensembl ID ENSG00000163655 Transcript ID ENST00000496455 Protein ID ENSP00000419851
Cancer types where is driver 1 Cohorts where is driver 1 Mutated samples 4 Mutations 214
Mode of action Activating
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence