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GMPPA has not been detected as a mutational cancer driver

GMPPA
Ensembl id ENSG00000144591
Mutated samples
Coding Sequence 36 (0.5%)
Protein Affecting 22 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all GMPPA gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 5 5 1.28
Breast carcinoma No 4 3 0.26
Cutaneous melanoma No 10 3 0.81
Stomach adenocarcinoma No 3 3 1.86
Lung squamous cell carcinoma No 2 2 1.15
Uterine corpus endometrioid carcinoma No 3 2 0.87
Neuroblastoma No 1 1 0.48
Non small cell lung carcinoma No 1 1 3.23
Colorectal adenocarcinoma No 1 1 0.44
Head and neck squamous cell carcinoma No 2 1 0.27
Bladder carcinoma No 1 0 0.00
Pylocytic astrocytoma No 2 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence