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GC has not been detected as a mutational cancer driver

GC
Ensembl id ENSG00000145321
Mutated samples
Coding Sequence 64 (0.9%)
Protein Affecting 50 (0.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all GC gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 17 13 3.52
Lung adenocarcinoma No 9 7 1.79
Head and neck squamous cell carcinoma No 9 6 1.60
Lung squamous cell carcinoma No 5 5 2.87
Bladder carcinoma No 3 3 3.06
Uterine corpus endometrioid carcinoma No 3 3 1.30
Stomach adenocarcinoma No 4 3 1.86
Serous ovarian adenocarcinoma No 2 2 0.63
Small cell lung carcinoma No 2 2 2.90
Glioblastoma multiforme No 2 2 0.53
Breast carcinoma No 1 1 0.09
Neuroblastoma No 1 1 0.48
Non small cell lung carcinoma No 1 1 3.23
Colorectal adenocarcinoma No 2 1 0.44
Prostate adenocarcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence