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GALNT5 has not been detected as a mutational cancer driver

GALNT5
Ensembl id ENSG00000136542
Mutated samples
Coding Sequence 78 (1.1%)
Protein Affecting 58 (0.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all GALNT5 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 19 12 3.25
Breast carcinoma No 7 5 0.44
Lung squamous cell carcinoma No 6 5 2.87
Renal clear cell carcinoma No 5 5 1.20
Lung adenocarcinoma No 5 4 1.02
Uterine corpus endometrioid carcinoma No 4 4 1.74
Head and neck squamous cell carcinoma No 5 4 1.07
Bladder carcinoma No 3 3 3.06
Stomach adenocarcinoma No 3 3 1.86
Medulloblastoma No 3 2 0.95
Small cell lung carcinoma No 3 2 2.90
Colorectal adenocarcinoma No 3 2 0.87
Glioblastoma multiforme No 3 2 0.53
Hepatocarcinoma No 3 1 1.11
Neuroblastoma No 1 1 0.48
Multiple myeloma No 1 1 1.45
Lower grade glioma No 1 1 0.59
Esophageal carcinoma No 1 1 0.68
Pylocytic astrocytoma No 1 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence