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FHDC1 has not been detected as a mutational cancer driver

FHDC1
Ensembl id ENSG00000137460
Mutated samples
Coding Sequence 65 (1.0%)
Protein Affecting 52 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all FHDC1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 19 14 3.79
Uterine corpus endometrioid carcinoma No 6 6 2.61
Lung adenocarcinoma No 5 5 1.28
Lung squamous cell carcinoma No 5 5 2.87
Stomach adenocarcinoma No 4 4 2.48
Breast carcinoma No 5 3 0.26
Lower grade glioma No 2 2 1.18
Head and neck squamous cell carcinoma No 3 2 0.53
Glioblastoma multiforme No 4 2 0.53
Esophageal carcinoma No 2 2 1.37
Hepatocarcinoma No 1 1 1.11
Medulloblastoma No 1 1 0.48
Pancreas adenocarcinoma No 1 1 0.47
Serous ovarian adenocarcinoma No 1 1 0.32
Small cell lung carcinoma No 1 1 1.45
Colorectal adenocarcinoma No 1 1 0.44
Acute lymphocytic leukemia No 1 1 0.82
Prostate adenocarcinoma No 1 0 0.00
Bladder carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence