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FGA has not been detected as a mutational cancer driver

FGA
Ensembl id ENSG00000171560
Mutated samples
Coding Sequence 141 (2.1%)
Protein Affecting 112 (1.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all FGA gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 47 39 10.57
Lung adenocarcinoma No 8 7 1.79
Breast carcinoma No 7 7 0.61
Head and neck squamous cell carcinoma No 7 7 1.87
Bladder carcinoma No 7 6 6.12
Glioblastoma multiforme No 6 6 1.58
Medulloblastoma No 4 4 1.90
Lung squamous cell carcinoma No 6 4 2.30
Uterine corpus endometrioid carcinoma No 5 4 1.74
Colorectal adenocarcinoma No 4 4 1.75
Hepatocarcinoma No 5 3 3.33
Serous ovarian adenocarcinoma No 3 3 0.95
Stomach adenocarcinoma No 5 3 1.86
Small cell lung carcinoma No 5 3 4.35
Prostate adenocarcinoma No 3 2 0.82
Pancreas adenocarcinoma No 3 2 0.93
Non small cell lung carcinoma No 2 2 6.45
Renal clear cell carcinoma No 1 1 0.24
Thyroid carcinoma No 1 1 0.31
Neuroblastoma No 1 1 0.48
Chronic lymphocytic leukemia No 2 1 0.34
Lower grade glioma No 2 1 0.59
Esophageal carcinoma No 4 1 0.68
Multiple myeloma No 2 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence