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FCRL2 has not been detected as a mutational cancer driver

FCRL2
Ensembl id ENSG00000132704
Mutated samples
Coding Sequence 87 (1.3%)
Protein Affecting 58 (0.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all FCRL2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 18 11 2.98
Lung adenocarcinoma No 13 10 2.56
Lung squamous cell carcinoma No 10 7 4.02
Esophageal carcinoma No 10 6 4.11
Stomach adenocarcinoma No 6 5 3.11
Head and neck squamous cell carcinoma No 3 3 0.80
Bladder carcinoma No 2 2 2.04
Breast carcinoma No 2 2 0.17
Neuroblastoma No 2 2 0.95
Small cell lung carcinoma No 3 2 2.90
Glioblastoma multiforme No 3 2 0.53
Prostate adenocarcinoma No 1 1 0.41
Renal clear cell carcinoma No 1 1 0.24
Uterine corpus endometrioid carcinoma No 2 1 0.43
Multiple myeloma No 1 1 1.45
Serous ovarian adenocarcinoma No 1 1 0.32
Colorectal adenocarcinoma No 2 1 0.44
Hepatocarcinoma No 1 0 0.00
Pancreas adenocarcinoma No 1 0 0.00
Non small cell lung carcinoma No 3 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence