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FAM43A has not been detected as a mutational cancer driver

FAM43A
Ensembl id ENSG00000185112
Mutated samples
Coding Sequence 16 (0.2%)
Protein Affecting 13 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all FAM43A gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 2 2 0.54
Stomach adenocarcinoma No 2 2 1.24
Head and neck squamous cell carcinoma No 2 2 0.53
Lung adenocarcinoma No 1 1 0.26
Lung squamous cell carcinoma No 3 1 0.57
Non small cell lung carcinoma No 1 1 3.23
Multiple myeloma No 1 1 1.45
Small cell lung carcinoma No 1 1 1.45
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 1 1 0.68
Breast carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence