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FAM149A has not been detected as a mutational cancer driver

FAM149A
Ensembl id ENSG00000109794
Mutated samples
Coding Sequence 29 (0.4%)
Protein Affecting 19 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all FAM149A gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 7 6 1.63
Lung adenocarcinoma No 6 4 1.02
Breast carcinoma No 3 2 0.17
Lung squamous cell carcinoma No 2 2 1.15
Uterine corpus endometrioid carcinoma No 1 1 0.43
Stomach adenocarcinoma No 1 1 0.62
Colorectal adenocarcinoma No 3 1 0.44
Head and neck squamous cell carcinoma No 3 1 0.27
Acute lymphocytic leukemia No 1 1 0.82
Chronic lymphocytic leukemia No 1 0 0.00
Lower grade glioma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence